Travelling waves in a wound healing assay
Several authors have predicted that cell propagation in a number of biological contexts, for example, wound healing, tumour cell invasion, angiogenesis etc., occurs due to a constant speed travelling wave of invasion. The analyses of these models to arrive at this prediction is, in many cases, essentially an extension of the classical analysis of Fisher's equation. Here, we show that a very simple wound healing assay does indeed give rise to constant speed travelling waves. To our knowledge, this is the first verification of Fisher's equation in a medical context.
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|Item Type:||Journal Article|
|Keywords:||Fisher's equation, Human peritoneal mesothelial cells, Invasion waves|
|Divisions:||Past > QUT Faculties & Divisions > Faculty of Science and Technology|
Current > Institutes > Institute of Health and Biomedical Innovation
Current > Schools > School of Mathematical Sciences
|Copyright Owner:||Copyright 2004 Elsevier|
|Deposited On:||28 Apr 2008|
|Last Modified:||25 Sep 2012 12:08|
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