Experimental study of the deposition of combustion aerosols in the human respiratory tract

Morawska, Lidia, Hofmann, Werner, Hitchins-Loveday, Jane, Swanson, Cheryl E., & Mengersen, Kerrie L. (2005) Experimental study of the deposition of combustion aerosols in the human respiratory tract. Journal of Aerosol Science, 36(8), pp. 939-957.

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Abstract

The total deposition of environmental tobacco smoke (ETS), diesel and petrol smoke in the respiratory tract of 14 non-smokers between the ages of 20 and 30 was determined experimentally. A scanning mobility particle sizer (SMPS) measuring a size range of 0.016–0.626 micrometres was used to characterise the inhaled and exhaled aerosol during relaxed nasal breathing over a period of 10 min. The ETS, diesel, and petrol particles had average count median diameter (and geometric standard deviation) of 0.183 micrometres (1.7), 0.125 micrometres (1.7), and 0.069 micrometres (1.7), respectively. The average total number deposition of ETS was 36% (standard deviation 10%), of diesel smoke 30% (standard deviation 9%), and of petrol smoke 41% (standard deviation 8%). The analysis of the deposition patterns as a function of particle size for the three aerosols in each individual showed that there is a significant difference between each aerosol for a majority of individuals (12 out of 14). This is an important result as it indicates that differences persist regardless of inter-subject variability.

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ID Code: 3664
Item Type: Journal Article
Refereed: Yes
Keywords: Respiratory tract deposition, Combustion aerosols, Submicrometer particles, Nasal breathing, Petrol smoke, Diesel smoke, Environmental tobacco smoke
DOI: 10.1016/j.jaerosci.2005.03.015
ISSN: 0021-8502
Divisions: Past > QUT Faculties & Divisions > Faculty of Science and Technology
Copyright Owner: Copyright 2005 Elsevier
Copyright Statement: Reproduced in accordance with the copyright policy of the publisher.
Deposited On: 20 Jul 2006 00:00
Last Modified: 31 May 2016 23:05

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