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Application of micro CT and computation modeling in bone tissue engineering

Tuan, Barnabas Ho Saey & Hutmacher, Dietmar (2005) Application of micro CT and computation modeling in bone tissue engineering. Computer Aided Design, 37(11), pp. 1151-1161.

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Abstract

Computer aided technologies, medical imaging, and rapid prototyping has created new possibilities in biomedical engineering. The systematic variation of scaffold architecture as well as the mineralization inside a scaffold/bone construct can be studied using computer imaging technology and CAD/CAM and micro computed tomography (CT). In this paper, the potential of combining these technologies has been exploited in the study of scaffolds and osteochondral repair. Porosity, surface area per unit volume and the degree of interconnectivity were evaluated through imaging and computer aided manipulation of the scaffold scan data. For the osteochondral model, the spatial distribution and the degree of bone regeneration were evaluated. In this study the versatility of two softwares Mimics (Materialize), CTan and 3D realistic visualization (Skyscan) were assessed, too.

Impact and interest:

58 citations in Scopus
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42 citations in Web of Science®

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ID Code: 37510
Item Type: Journal Article
Keywords: Computer aided design; Medical imaging; Scaffolds; Bone engineering; Micro CT
DOI: 10.1016/j.cad.2005.02.006
ISSN: 0010-4485
Subjects: Australian and New Zealand Standard Research Classification > BIOLOGICAL SCIENCES (060000) > OTHER BIOLOGICAL SCIENCES (069900)
Australian and New Zealand Standard Research Classification > ENGINEERING (090000) > BIOMEDICAL ENGINEERING (090300)
Australian and New Zealand Standard Research Classification > ENGINEERING (090000) > MECHANICAL ENGINEERING (091300)
Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > MEDICAL PHYSIOLOGY (111600)
Australian and New Zealand Standard Research Classification > BUILT ENVIRONMENT AND DESIGN (120000) > DESIGN PRACTICE AND MANAGEMENT (120300)
Divisions: Past > QUT Faculties & Divisions > Faculty of Built Environment and Engineering
Deposited On: 30 Sep 2010 16:42
Last Modified: 29 Feb 2012 23:57

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