Exploring retinal and functional markers of diabetic neuropathy

Moavenshahidi, Ayda, Sampson, Geoff, Pritchard, Nicola, Edwards, Katie P., Russell, Anthony, Malik, Rayaz A., & Efron, Nathan (2010) Exploring retinal and functional markers of diabetic neuropathy. Clinical and Experimental Optometry, 93(5), pp. 309-323.

PDF (678kB)
Figures (PDF 536kB)
Supplemental Material.

View at publisher


Diabetic peripheral neuropathy (DPN) is one of the most debilitating complications of diabetes. DPN is a major cause of foot ulceration and lower limb amputation. Early diagnosis and management is a key factor in reducing morbidity and mortality. Current techniques for clinical assessment of DPN are relatively insensitive for detecting early disease or involve invasive procedures such as skin biopsies. There is a need for less painful, non-invasive and safe evaluation methods. Eye care professionals already play an important role in the management of diabetic retinopathy; however recent studies have indicated that the eye may also be an important site for the diagnosis and monitoring of neuropathy. Corneal nerve morphology has been shown to be a promising marker of diabetic neuropathy occurring elsewhere in the body, and emerging evidence tentatively suggests that retinal anatomical markers and a range of functional visual indicators could similarly provide useful information regarding neural damage in diabetes – although this line of research is, as yet, less well established. This review outlines the growing body of evidence supporting a potential diagnostic role for retinal structure and visual functional markers in the diagnosis and monitoring of peripheral neuropathy in diabetes.

Impact and interest:

7 citations in Scopus
6 citations in Web of Science®
Search Google Scholar™

Citation counts are sourced monthly from Scopus and Web of Science® citation databases.

These databases contain citations from different subsets of available publications and different time periods and thus the citation count from each is usually different. Some works are not in either database and no count is displayed. Scopus includes citations from articles published in 1996 onwards, and Web of Science® generally from 1980 onwards.

Citations counts from the Google Scholar™ indexing service can be viewed at the linked Google Scholar™ search.

Full-text downloads:

508 since deposited on 10 Nov 2010
18 in the past twelve months

Full-text downloads displays the total number of times this work’s files (e.g., a PDF) have been downloaded from QUT ePrints as well as the number of downloads in the previous 365 days. The count includes downloads for all files if a work has more than one.

ID Code: 38384
Item Type: Journal Article
Refereed: Yes
Keywords: Diabetes Mellitus, Optical Coherence Tomography, Peripheral Neuropathy, Retina, Visual Fields, Visual Function
DOI: 10.1111/j.1444-0938.2010.00491.x
ISSN: 0816-4622
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300)
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 2010 Wiley-Blackwell Publishing Ltd.
Deposited On: 10 Nov 2010 01:26
Last Modified: 21 Jun 2017 14:44

Export: EndNote | Dublin Core | BibTeX

Repository Staff Only: item control page