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Photo-crosslinking of functionalised lactide oligomers for the fabrication of osteochondral tissue engineering scaffolds

Melchels, F.P.W., Grijpma, D.W., & Feijen, J. (2006) Photo-crosslinking of functionalised lactide oligomers for the fabrication of osteochondral tissue engineering scaffolds. In Journal of Controlled Release, Elsevier BV, Noordwijk, Netherlands, e98-e100.

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    Abstract

    In the fabrication of osteochondral tissue engineering scaffolds, the two distinct tissues impose different requirements on the architecture. Stereo-lithography is a rapid prototyping method that can be utilised to make 3D constructs with high spatial control by radical photopolymerization. In this study, biodegradable resins are developed that can be applied in stereo-lithography. Photo-crosslinked poly(lactide) networks with varying physical properties were synthesised, and by photo polymerizing in the presence of leachable particles porous scaffolds could be prepared as well.

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    ID Code: 38880
    Item Type: Conference Paper
    Keywords: osteochondral tissue engineering scaffolds, stereo-lithography, rapid prototyping, 3D constructs, radical photopolymerization
    DOI: 10.1016/j.jconrel.2006.09.070
    ISSN: 0168-3659
    Subjects: Australian and New Zealand Standard Research Classification > ENGINEERING (090000) > BIOMEDICAL ENGINEERING (090300) > Biomaterials (090301)
    Divisions: Past > QUT Faculties & Divisions > Faculty of Built Environment and Engineering
    Current > Institutes > Institute of Health and Biomedical Innovation
    Past > Schools > School of Engineering Systems
    Copyright Owner: Copyright 2006 Published by Elsevier B.V.
    Deposited On: 25 Nov 2010 15:02
    Last Modified: 04 Jul 2012 08:42

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