Development of a PDLLA-based stereolithography resin for making tissue engineering scaffolds
Melchels, F.P.W., Grijpma, D.W., & Feijen, J. (2007) Development of a PDLLA-based stereolithography resin for making tissue engineering scaffolds. In 16th Annual Meeting of the Netherlands Society for Biomaterials and Tissue Engineering, 2007, Lunteren, Netherlands.
The use of porous structures as tissue engineering scaffolds imposes high demands on the pore architecture. Stereolithography is a rapid prototyping method based on photo-polymerisation, that can be utilised to make 3D constructs with high spatial control. In this study, biodegradable resins were developed that can find application in stereolithography. Poly(D,L-lactide) (PDLLA) oligomers were synthesised and functionalised with methacrylate end-groups. By mixing the resulting macromers with a diluent, photo-initiator and inhibitor, lowviscosity resins were obtained that were photocrosslinked to yield stiff and strong degradable poly(lactide) networks. Also, porous scaffolds were fabricated on a stereolithography apparatus (SLA) from a nondegradable resin.
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|Item Type:||Conference Paper|
|Subjects:||Australian and New Zealand Standard Research Classification > ENGINEERING (090000) > BIOMEDICAL ENGINEERING (090300) > Biomaterials (090301)|
|Divisions:||Past > QUT Faculties & Divisions > Faculty of Built Environment and Engineering|
Current > Institutes > Institute of Health and Biomedical Innovation
Past > Schools > School of Engineering Systems
|Copyright Owner:||Copyright 2007 Please consult the authors.|
|Deposited On:||02 Dec 2010 13:39|
|Last Modified:||04 Jul 2012 10:52|
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