Designed poly(ethylene glycol)/poly(D,L-lactide)-based hydrogel structures prepared by stereolithography

Seck, Tetsu M., Melchels, Ferry P.W., Feijen, Jan, & Grijpma, Dirk W. (2010) Designed poly(ethylene glycol)/poly(D,L-lactide)-based hydrogel structures prepared by stereolithography. In 11th European Symposium on Controlled Drug Delivery, 6-9 April 2010, Egmond aan Zee, Netherlands.

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Abstract

Three-dimensional biodegradable poly(ethylene glycol)/poly(D,L-lactide) hydrogel structures were prepared by stereolithography. A photo-polymerisable liquid resin comprising PDLLA-PEG-PDLLA-based macromer, visible light photo-initiator, dye and inhibitor in DMSO/water was used to build the structures. Hydrogels with welldefined architectures and good mechanical properties were prepared. Hydrogel structures with a gyroid pore network architecture showed narrow pore size distributions, excellent pore interconnectivity and good mechanical properties. The structures showed good cell seeding characteristics, and human mesenchymal stem cells adhered and proliferated on these materials.

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ID Code: 39018
Item Type: Conference Paper
Subjects: Australian and New Zealand Standard Research Classification > ENGINEERING (090000) > BIOMEDICAL ENGINEERING (090300) > Biomaterials (090301)
Divisions: Past > QUT Faculties & Divisions > Faculty of Built Environment and Engineering
Current > Institutes > Institute of Health and Biomedical Innovation
Past > Schools > School of Engineering Systems
Copyright Owner: Copyright 2010 Please consult the authors.
Deposited On: 03 Dec 2010 06:45
Last Modified: 10 Aug 2011 17:20

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