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Can proteoglycan change in articular cartilage be detected by ultrasound evaluation?

Afara, Isaac O., Wallace, Sam, Singh, Sanjleena, & Oloyede, Adekunle (2013) Can proteoglycan change in articular cartilage be detected by ultrasound evaluation? In Nondestructive Testing of Materials and Structures: Proceedings of NDTMS-2011 [RILEM Bookseries, 2013, Volume 6], Springer, Suleyman Demirel Cultural Center, Istanbul, Turkey, pp. 393-398.

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Abstract

This paper assesses the capacity of high-frequency ultrasonic waves for detecting changes in the proteoglycan (PG) content of articular cartilage. 50 cartilage-on-bone samples were exposed to ultrasonic waves via an ultrasound transducer at a frequency of 20MHz. Histology and ImageJ processing were conducted to determine the PG content of the specimen. The ratios of the reflected signals from both the surface and the osteochondral junction (OCJ) were determined from the experimental data. The initial results show an inconsistency in the capacity of ultrasound to distinguish samples with severe proteoglycan loss (i.e. >90% PG loss) from the normal intact sample. This lack of clear distinction was also demonstrated at for samples with less than 60% depletion, while there is a clear differentiation between the normal intact sample and those with 55-70% PG loss.

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ID Code: 39749
Item Type: Conference Paper
Keywords: articular cartilage, ultrasound reflection ratio
DOI: 10.1007/978-94-007-0723-8_57
ISBN: 978-94-007-0722-1
Subjects: Australian and New Zealand Standard Research Classification > ENGINEERING (090000) > BIOMEDICAL ENGINEERING (090300)
Australian and New Zealand Standard Research Classification > ENGINEERING (090000) > BIOMEDICAL ENGINEERING (090300) > Medical Devices (090304)
Divisions: Past > QUT Faculties & Divisions > Faculty of Built Environment and Engineering
Current > Institutes > Institute of Health and Biomedical Innovation
Past > Schools > School of Engineering Systems
Copyright Owner: Copyright 2011 [please consult the authors]
Deposited On: 31 Jan 2011 07:32
Last Modified: 19 Apr 2013 08:02

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