Time-dependent analysis of length of stay and mortality due urinary tract infections in ten developing countries : INICC findings

Rosenthal, V.D., Dwivedy, A., Rodríguez Calderón, M.E., Esen, S., Hernández, H.T., Abouqal, R., Medeiros, E.A., Espinoza, T.A., Kanj, S.S., Gikas, A., Barnett, A.G., & Graves, N. (2010) Time-dependent analysis of length of stay and mortality due urinary tract infections in ten developing countries : INICC findings. Journal of Infection, 62(2), pp. 136-141.

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Catheter associated urinary tract infections (CAUTI) are a worldwide problem that may lead to increased patient morbidity, cost and mortality.1e3 The literature is divided on whether there are real effects from CAUTI on length of stay or mortality. Platt4 found the costs and mortality risks to be largeyetGraves et al found the opposite.5 A reviewof the published estimates of the extra length of stay showed results between zero and 30 days.6 The differences in estimates may have been caused by the different epidemiological methods applied. Accurately estimating the effects of CAUTI is difficult because it is a time-dependent exposure. This means that standard statistical techniques, such asmatched case-control studies, tend to overestimate the increased hospital stay and mortality risk due to infection. The aim of the study was to estimate excess length of stay andmortality in an intensive care unit (ICU) due to a CAUTI, using a statistical model that accounts for the timing of infection. Data collected from ICU units in lower and middle income countries were used for this analysis.7,8 There has been little research for these settings, hence the need for this paper.

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11 citations in Web of Science®
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ID Code: 39860
Item Type: Journal Article
Refereed: Yes
Keywords: International Nosocomial Infection Control Consortium, INICC, Urinary Tract Infections, Length of Stay, Mortality, Developing Countries, Intensive Care Unit, Time-dependent Analysis, Hospital Infection, Nosocomial Infection
DOI: 10.1016/j.jinf.2010.12.004
ISSN: 0163-4453
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > PUBLIC HEALTH AND HEALTH SERVICES (111700)
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Current > Schools > School of Public Health & Social Work
Copyright Owner: Copyright 2011 The British Infection Association Published by Elsevier Ltd.
Deposited On: 03 Feb 2011 01:48
Last Modified: 29 Feb 2012 14:28

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