In silico experimental modeling of cancer treatment

Mallet, Daniel G. & Trisilowati, (2012) In silico experimental modeling of cancer treatment. ISRN Oncology, 2012.

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In silico experimental modeling of cancer involves combining findings from biological literature with computer-based models of biological systems in order to conduct investigations of hypotheses entirely in the computer laboratory. In this paper, we discuss the use of in silico modeling as a precursor to traditional clinical and laboratory research, allowing researchers to refine their experimental programs with an aim to reducing costs and increasing research efficiency. We explain the methodology of in silico experimental trials before providing an example of in silico modeling from the biomathematical literature with a view to promoting more widespread use and understanding of this research strategy.

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117 since deposited on 01 Jul 2011
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ID Code: 42331
Item Type: Journal Article
Refereed: Yes
Keywords: in silico, mathematical modeling, computational biology, cellular automata
DOI: 10.5402/2012/828701
ISSN: 2090-567X
Subjects: Australian and New Zealand Standard Research Classification > MATHEMATICAL SCIENCES (010000) > APPLIED MATHEMATICS (010200) > Biological Mathematics (010202)
Divisions: Past > QUT Faculties & Divisions > Faculty of Science and Technology
Current > Institutes > Institute of Health and Biomedical Innovation
Past > Schools > Mathematical Sciences
Copyright Owner: Copyright 2012 Hindawi Publishing
Deposited On: 01 Jul 2011 01:01
Last Modified: 15 May 2012 03:05

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