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Assessment of corneal dynamics with high-speed swept source optical coherence tomography combined with an air puff system

Alonso-Caneiro, David, Karnowski, Karol , Kaluzny, Bartlomiej J. , Kowalczyk, Andrzej , & Wojtkowski, Maciej (2011) Assessment of corneal dynamics with high-speed swept source optical coherence tomography combined with an air puff system. Optics Express, 19(15), pp. 14188-14199.

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Abstract

We present a novel method and instrument for in vivo imaging and measurement of the human corneal dynamics during an air puff. The instrument is based on high-speed swept source optical coherence tomography (ssOCT) combined with a custom adapted air puff chamber from a non-contact tonometer, which uses an air stream to deform the cornea in a non-invasive manner. During the short period of time that the deformation takes place, the ssOCT acquires multiple A-scans in time (M-scan) at the center of the air puff, allowing observation of the dynamics of the anterior and posterior corneal surfaces as well as the anterior lens surface. The dynamics of the measurement are driven by the biomechanical properties of the human eye as well as its intraocular pressure. Thus, the analysis of the M-scan may provide useful information about the biomechanical behavior of the anterior segment during the applanation caused by the air puff. An initial set of controlled clinical experiments are shown to comprehend the performance of the instrument and its potential applicability to further understand the eye biomechanics and intraocular pressure measurements. Limitations and possibilities of the new apparatus are discussed.

Impact and interest:

11 citations in Scopus
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11 citations in Web of Science®

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ID Code: 42617
Item Type: Journal Article
Keywords: Optical Coherence Tomography, non-contact tonometer, corneal dynamics, swept source Optical Coherence Tomography
DOI: 10.1364/OE.19.014188
ISSN: 1094-4087
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300) > Optical Technology (111302)
Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300) > Vision Science (111303)
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 2011 Optical Society of America
Copyright Statement: This paper was published in Optics Express and is made available as an electronic reprint with the permission of OSA. The paper can be found at the following URL on the OSA website: http://www.opticsinfobase.org/oe/abstract.cfm?uri=oe-19-15-14188. Systematic or multiple reproduction or distribution to multiple locations via electronic or other means is prohibited and is subject to penalties under law.
Deposited On: 14 Jul 2011 09:04
Last Modified: 31 Oct 2011 11:05

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