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A parametric approach to measuring limbus corneae from digital images

Iskander, D. Robert (2006) A parametric approach to measuring limbus corneae from digital images. IEEE Transactions on Biomedical Engineering, 53(6), pp. 1134-1140.

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Abstract

It is difficult to demarcate the limbus borders in standard intensity images of the eye since the transition from the cornea (iris) to sclera is gradual. Non-parametric techniques that are currently used for this task are not sufficiently precise to be adopted in those ophthalmic applications where high precision in determining the limbus/pupil characteristics is required. This is the case, for example, in customized refractive corrections. Another aspect of limbus corneae characterization is the inability of measuring in vivo the outer outline of the limbus annulus without specialized illumination techniques. To overcome these limitations, we propose a parametric approach that utilizes a sigmoidal function fitted to radial intensity profiles of the limbus corneae. By the way of simulations, we show the superiority of the proposed parametric approach when compared to an optimized nonparametric technique. Further, we review the techniques for fitting ellipses to the estimated points of the limbus annulus and discuss clinical aspects of the proposed methodology. Initial clinical experiments showed close agreement between the proposed approach and limbus corneae estimates manually obtained by experienced clinicians.

Impact and interest:

8 citations in Scopus
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6 citations in Web of Science®

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ID Code: 4426
Item Type: Journal Article
Keywords: horizontal corneal diameter, horizontal visible iris diameter, limbus size, pupillometry, sigmoidal function, white, to, white corneal diameter
DOI: 10.1109/TBME.2006.873387
ISSN: 0018-9294
Subjects: Australian and New Zealand Standard Research Classification > PHYSICAL SCIENCES (020000) > OTHER PHYSICAL SCIENCES (029900) > Medical Physics (029903)
Australian and New Zealand Standard Research Classification > ENGINEERING (090000) > BIOMEDICAL ENGINEERING (090300) > Biomedical Instrumentation (090303)
Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300) > Vision Science (111303)
Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300) > Optical Technology (111302)
Australian and New Zealand Standard Research Classification > INFORMATION AND COMPUTING SCIENCES (080000) > COMPUTER SOFTWARE (080300) > Computer Software not elsewhere classified (080399)
Divisions: Past > QUT Faculties & Divisions > Faculty of Built Environment and Engineering
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 2006 IEEE
Copyright Statement: Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from the IEEE.
Deposited On: 05 Jul 2006
Last Modified: 29 Feb 2012 23:23

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