A genome-based strategy uncovers frequent BRAF mutations in melanoma
Pollock, Pamela M. & Meltzer, Paul S. (2002) A genome-based strategy uncovers frequent BRAF mutations in melanoma. Cancer Cell, 2(1), pp. 5-7.
Using a genome-scanning approach to search for oncogenes, a recent report identifies somatic mutations in the signaling gene BRAF that are particularly prevalent in melanoma.
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|Item Type:||Journal Article|
|Keywords:||Cell Transformation, Neoplastic, Humans, Melanoma/enzymology/ genetics/metabolism/pathology, Mitogen-Activated Protein Kinases/metabolism, Models, Biological, Mutation, Point Mutation/genetics, Protein Structure, Tertiary, Proto-Oncogene Proteins B-raf, Proto-Oncogene Proteins c-raf/chemistry/ genetics/metabolism, Signal Transduction, Tumor Cells, Cultured, ras Proteins/metabolism|
|Subjects:||Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > ONCOLOGY AND CARCINOGENESIS (111200) > Cancer Cell Biology (111201)|
|Divisions:||Past > Schools > Cell & Molecular Biosciences
Past > QUT Faculties & Divisions > Faculty of Science and Technology
Current > Institutes > Institute of Health and Biomedical Innovation
|Deposited On:||09 Sep 2011 04:33|
|Last Modified:||09 Sep 2011 04:33|
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