Profluorescent nitroxides as sensitive probes of oxidative change and free radical reactions
Blinco, James P., Fairfull-Smith, Kathryn E., Morrow, Benjamin J., & Bottle, Steven E. (2011) Profluorescent nitroxides as sensitive probes of oxidative change and free radical reactions. Australian Journal of Chemistry, 64(4), pp. 373-389.
This paper presents a review on the use of tethered nitroxide–fluorophore molecules as probes of oxidative change and free radical generation and reaction. The proximity of the nitroxide free radical to the fluorophore suppresses the normal fluorescence emission process. Nitroxide free radical scavenging, metabolism or redox chemistry return the system to its natural fluorescent state and so these tethered nitroxide–fluorophore molecules are described as being profluorescent. A survey of profluorescent nitroxides found in the literature is provided as well as background on the mechanism of action and applications of these compounds as fluorometric probes within the fields of biological, materials and environmental sciences.
Impact and interest:
Citation counts are sourced monthly from and citation databases.
Citations counts from theindexing service can be viewed at the linked Google Scholar™ search.
|Item Type:||Journal Article|
|Keywords:||tethered nitroxide–fluorophore, oxidative change, fluorophore|
|Subjects:||Australian and New Zealand Standard Research Classification > CHEMICAL SCIENCE (030000) > MACROMOLECULAR AND MATERIALS CHEMISTRY (030300)
Australian and New Zealand Standard Research Classification > CHEMICAL SCIENCE (030000) > ORGANIC CHEMISTRY (030500) > Free Radical Chemistry (030501)
|Divisions:||Past > Schools > Chemistry
Past > QUT Faculties & Divisions > Faculty of Science and Technology
|Deposited On:||12 Sep 2011 22:58|
|Last Modified:||12 Sep 2011 22:58|
Repository Staff Only: item control page