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Transglutaminases and receptor tyrosine kinases

Sivaramakrishnan, Manaswini, Shooter, Gary K., Upton, Zee, & Croll, Tristan I. (2011) Transglutaminases and receptor tyrosine kinases. .

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    Abstract

    Transglutaminases are confounding enzymes which are known to play key roles in various cellular processes. In this paper, we aim to bring together several pieces of evidence from published research and literature that suggest a potentially vital role for transglutaminases in receptor tyrosine kinases (RTK) signalling. We cite literature that confirm and suggest the formation of integrin:RTK:transglutaminase complexes and explore the occurrence and functionality of these complexes in a large fraction of the RTK family.

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    ID Code: 46261
    Item Type: Journal Article
    Additional Information: This article is submitted to Amino Acids (Springer) for publication.
    Keywords: Transglutaminases, Receptor Tyrosine Kinases, Extracellular Matrix, Membrane Biology
    Subjects: Australian and New Zealand Standard Research Classification > BIOLOGICAL SCIENCES (060000) > BIOCHEMISTRY AND CELL BIOLOGY (060100) > Cellular Interactions (incl. Adhesion Matrix Cell Wall) (060106)
    Australian and New Zealand Standard Research Classification > BIOLOGICAL SCIENCES (060000) > BIOCHEMISTRY AND CELL BIOLOGY (060100) > Receptors and Membrane Biology (060110)
    Divisions: Past > Schools > Cell & Molecular Biosciences
    Past > QUT Faculties & Divisions > Faculty of Science and Technology
    Current > Institutes > Institute of Health and Biomedical Innovation
    Copyright Owner: Copyright 2011 The Authors
    Deposited On: 03 Oct 2011 11:08
    Last Modified: 03 Oct 2011 20:32

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