Transglutaminases and receptor tyrosine kinases

Sivaramakrishnan, Manaswini, Shooter, Gary K., Upton, Zee, & Croll, Tristan I. (2013) Transglutaminases and receptor tyrosine kinases. Amino Acids, 44(1), pp. 19-24.

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Transglutaminases are confounding enzymes which are known to play key roles in various cellular processes. In this paper, we aim to bring together several pieces of evidence from published research and literature that suggest a potentially vital role for transglutaminases in receptor tyrosine kinases (RTK) signalling. We cite literature that confirms and suggests the formation of integrin:RTK:transglutaminase complexes and explores the occurrence and functionality of these complexes in a large fraction of the RTK family.

Impact and interest:

5 citations in Scopus
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6 citations in Web of Science®

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254 since deposited on 03 Oct 2011
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ID Code: 46261
Item Type: Journal Article
Refereed: Yes
Keywords: Transglutaminases, Receptor Tyrosine Kinases, Extracellular Matrix, Membrane Biology, Integrins, Fibronectin, Tissue transglutaminase
DOI: 10.1007/s00726-011-1113-x
ISSN: 0939-4451
Subjects: Australian and New Zealand Standard Research Classification > BIOLOGICAL SCIENCES (060000) > BIOCHEMISTRY AND CELL BIOLOGY (060100) > Cellular Interactions (incl. Adhesion Matrix Cell Wall) (060106)
Australian and New Zealand Standard Research Classification > BIOLOGICAL SCIENCES (060000) > BIOCHEMISTRY AND CELL BIOLOGY (060100) > Receptors and Membrane Biology (060110)
Divisions: Past > Schools > Cell & Molecular Biosciences
Past > QUT Faculties & Divisions > Faculty of Science and Technology
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 2011 Springer-Verlag
Copyright Statement: The final publication is available at
Deposited On: 03 Oct 2011 01:08
Last Modified: 05 Sep 2013 00:45

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