Substance-induced psychosis : a diagnostic conundrum

Mathias, S., Lubman, D.I., & Hides, L. (2008) Substance-induced psychosis : a diagnostic conundrum. Journal of Clinical Psychiatry, 69(3), pp. 358-367.

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Objective: To critically examine the DSM-IV-TR criteria for Substance-Induced Psychotic Disorder (SIPD).

Data sources: Leading electronic databases (such as Medline, Pubmed) were searched for the years 1992 through 2007, using combinations of the following key search terms: substance abuse/dependence, alcohol, marijuana, cannabis, methamphetamine, crack, cocaine, amphetamine, ecstasy, ketamine, phencyclidine, LSD, mental health, drug-induced psychosis, substance-induced psychosis, psychosis, schizophrenia. References identified from bibliographies of pertinent articles and books in the field were also collected and reviewed.

Data extraction: Only research studies or case reports series that presented data on populations diagnosed with SIPD using clinical or structured diagnostic interviews published in English were used to assess the validity of the current SIPD criteria.

Data synthesis: We identified 49 articles that presented clinical data on SIPD. The majority of these publications were case reports, with only 18 articles specifically focusing on delineating the clinical characteristics or outcomes of individuals diagnosed with SIPD. While several large studies have recently been conducted to assess the stability of SIPD, there is a dearth of research rigorously examining the validity of DSM-IV diagnostic criteria across substances.

Conclusions: There remains a striking paucity of information on the outcome, treatment and best practice for substance-associated psychotic episodes. Further work is clearly required before the advent of DSM-V. We propose an alternative, broader classification that better reflects the current evidence base, inferring association rather than causation.

Impact and interest:

58 citations in Scopus
49 citations in Web of Science®
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ID Code: 46581
Item Type: Journal Article
Refereed: Yes
Additional URLs:
Keywords: substance-induced psychotic disorder (SIPD)
ISSN: 0160-6689
Subjects: Australian and New Zealand Standard Research Classification > PSYCHOLOGY AND COGNITIVE SCIENCES (170000) > PSYCHOLOGY (170100)
Divisions: Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 2011 Physicians Postgraduate Press, Inc.
Deposited On: 23 Oct 2011 22:47
Last Modified: 29 Feb 2012 14:37

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