Hafner, Louise M. & Timms, Peter (2013) Chlamydia. In Stanberry, Lawrence R. & Rosenthal, Susan L. (Eds.) Sexually Transmitted Diseases : Vaccines, Prevention, and Control (Second Edition). Elsevier, Waltham, Mass, pp. 369-410.

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Chlamydial infections of humans can cause blindness and infertility as a result of diseases such as keratoconjunctivitis (trachoma), urethritis and cervicitis. However, in greater than half of all chlamydial diseases in males and females there are no signs or symptoms of infection. Chlamydia trachomatis is the causative bacterial organism responsible for the global estimate of 40.6 million people currently suffering with active trachoma and for the five million new cases of sexually transmitted infections each year in the United States of America. Even though antibiotics are available to treat Chlamydia, the incidence of each of these primarily asymptomatic infections continues to increase. In this Chapter we review the current knowledge of C.trachomatis including clinicial diseases and sequelae, the chlamydial developmental cycle in vivo, immunobiology and immune responses to infections, chlamydial genomics and vaccine development.

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ID Code: 47925
Item Type: Book Chapter
Keywords: Chlamydia trachomatis, Vaccine Development
DOI: 10.1016/B978-0-12-391059-2.00015-2
ISBN: 9780123910592
Subjects: Australian and New Zealand Standard Research Classification > BIOLOGICAL SCIENCES (060000) > MICROBIOLOGY (060500) > Infectious Agents (060502)
Divisions: Past > Schools > Cell & Molecular Biosciences
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 2013 Elsevier Ltd.
Deposited On: 04 Jan 2012 01:54
Last Modified: 14 Dec 2015 04:18

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