4-(4-Aminophenylsulfonyl)aniline-3,5-dinitrobenzoic acid (1/1)
Smith, Graham & Wermuth, Urs D. (2012) 4-(4-Aminophenylsulfonyl)aniline-3,5-dinitrobenzoic acid (1/1). Acta Crystallographica. Section E : Structure Reports Online, 68, o669-o669.
In the title co-crystalline adduct of the drug Dapsone with 3,5-dinitrobenzoic acid, C~12~H~12~N~2~O~2~S . C~7~H~4~N~4~O~6~, the dihedral angle between the two aromatic rings of the Dapsone molecule is 75.4(2)deg. and those between these rings and that of the 3,5-dinitrobenzoic acid are 64.5(2) and 68.4(2)deg.
A strong inter-species carboxylic acid O-H---N(amine) hydrogen-bond is found, which together with intermolecular amine N-H...O hydrogen-bonding associations with carboxyl, nitro and sulfone O-atom acceptors as well as weak pi-pi interactions between one of the Dapsone phenyl rings and the 3,5-dinitrobenzoic acid ring [minimum ring centroid separation 3.774(2)Ang.], give a two-dimensional network structure.
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|Item Type:||Journal Article|
|Keywords:||crystal structure, hydrogen bonding, Dapsone, molecular adduct|
|Subjects:||Australian and New Zealand Standard Research Classification > CHEMICAL SCIENCE (030000) > PHYSICAL CHEMISTRY (INCL. STRUCTURAL) (030600) > Structural Chemistry and Spectroscopy (030606)|
|Divisions:||Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > QUT Faculties and Divisions > Science & Engineering Faculty
|Copyright Owner:||Copyright 2012 IUCr|
|Copyright Statement:||This open-access article is distributed under the terms of the Creative Commons Attribution Licence http://creativecommons.org/licenses/by/2.0/uk/legalcode, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.|
|Deposited On:||23 Feb 2012 23:17|
|Last Modified:||18 Apr 2013 08:04|
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