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MRI study of the changes in crystalline lens shape with accommodation and ageing in humans

Kasthurirangan, Sanjeev, Markwell, Emma L., Atchison, David A., & Pope, James M. (2011) MRI study of the changes in crystalline lens shape with accommodation and ageing in humans. Journal of Vision, 11(3), p. 19.

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Abstract

Magnetic Resonance Imaging was used to study changes in the crystalline lens and ciliary body with accommodation and aging. Monocular images were obtained in 15 young (19-29 years) and 15 older (60-70 years) emmetropes when viewing at far (6m) and at individual near points (14.5 to 20.9 cm) in the younger group. With accommodation, lens thickness increased (mean±95% CI: 0.33±0.06mm) by a similar magnitude to the decrease in anterior chamber depth (0.31±0.07mm) and equatorial diameter (0.32±0.04mm) with a decrease in the radius of curvature of the posterior lens surface (0.58±0.30mm). Anterior lens surface shape could not be determined due to the overlapping region with the iris. Ciliary ring diameter decreased (0.44±0.17mm) with no decrease in circumlental space or forward ciliary body movement. With aging, lens thickness increased (mean±95% CI: 0.97±0.24mm) similar in magnitude to the sum of the decrease in anterior chamber depth (0.45±0.21mm) and increase in anterior segment depth (0.52±0.23mm). Equatorial lens diameter increased (0.28±0.23mm) with no change in the posterior lens surface radius of curvature. Ciliary ring diameter decreased (0.57±0.41mm) with reduced circumlental space (0.43±0.15mm) and no forward ciliary body movement. Accommodative changes support the Helmholtz theory of accommodation including an increase in posterior lens surface curvature. Certain aspects of aging changes mimic accommodation.

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8 citations in Web of Science®

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ID Code: 49189
Item Type: Journal Article
Keywords: Presbyopia, accommodation restoration, cataract surgery, equatorial diameter, radius of curvature , anterior chamber depth, anterior segment length, asphericity , lens thickness, mechanism of accommodation, ocular parameters, lens
DOI: 10.1167/11.3.19
ISSN: 1534-7362
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000)
Divisions: Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Current > QUT Faculties and Divisions > Science & Engineering Faculty
Current > Schools > School of Optometry & Vision Science
Copyright Owner: Copyright 2011 The Association for Research in Vision and Ophthalmology (ARVO)
Deposited On: 20 Mar 2012 09:40
Last Modified: 20 Mar 2012 10:04

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