Geologically ancient DNA: fact or artefact?
Hebsgaard, Martin B. , Phillips, Matthew J., & Willerslev, Eske (2005) Geologically ancient DNA: fact or artefact? Trends in Microbiology, 13(5), pp. 212-220.
Studies continue to report ancient DNA sequences and viable microbial cells that are many millions of years old. In this paper we evaluate some of the most extravagant claims of geologically ancient DNA. We conclude that although exciting, the reports suffer from inadequate experimental setup and insufficient authentication of results. Consequently, it remains doubtful whether amplifiable DNA sequences and viable bacteria can survive over geological timescales. To enhance the credibility of future studies and assist in discarding false-positive results, we propose a rigorous set of authentication criteria for work with geologically ancient DNA.
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|Item Type:||Journal Article|
|Subjects:||Australian and New Zealand Standard Research Classification > BIOLOGICAL SCIENCES (060000) > MICROBIOLOGY (060500)|
|Copyright Owner:||Copyright 2005 Elsevier Ltd.|
|Deposited On:||23 May 2012 13:20|
|Last Modified:||23 May 2012 13:20|
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