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Regulation of proteasome structure and function

Rivett, A.Jennifer, Mason, Grant, Murray, Rachael, & Reidlinger, Jutta (1997) Regulation of proteasome structure and function. Molecular Biology Reports, 24, pp. 99-102.

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Abstract

Proteasomes are cylindrical particles made up of a stack of four heptameric rings. In animal cells the outer rings are made up of 7 different types of alpha subunits and the inner rings are composed of 7 out of 10 possible different beta subunits. Regulatory complexes can bind to the ends of the cylinder.We have investigated aspects of the assembly, activity and subunit composition of core proteasome particles and 26S proteasomes, the localization of proteasome subpopulations, and the possible role of phosphorylation in determining proteasome localization, activities and association with regulatory components.

Impact and interest:

25 citations in Scopus
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26 citations in Web of Science®

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ID Code: 50547
Item Type: Journal Article
Keywords: proteasome assembly, catalytic components, processing of beta subunits, localization
DOI: 10.1023/A:1006814306401
ISSN: 0301-4851
Subjects: Australian and New Zealand Standard Research Classification > BIOLOGICAL SCIENCES (060000) > BIOCHEMISTRY AND CELL BIOLOGY (060100) > Enzymes (060107)
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Deposited On: 23 May 2012 11:27
Last Modified: 23 May 2012 11:27

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