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Porous Ca-Si-based nanospheres : a potential intra-canal disinfectant-carrier for infected canal treatment

Fan , Wei, Wu, Chengtie, Han , Pingping, Zhou, Yinghong, & Xiao, Yin (2012) Porous Ca-Si-based nanospheres : a potential intra-canal disinfectant-carrier for infected canal treatment. Materials Letters, 81, pp. 16-19.

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Abstract

The aim of this study is to develop a new intra-canal disinfectant-carrier for infected canal treatment. To achieve this purpose, a new porous Ca-Si (CS)-based nanosphere was synthesized and characterized. Results showed that the nanospheres can infiltrate into dentinal tubules and released the ampicillin over one week time in a sustained manner. The release of ampicillin from spheres has significantly antibacterial property. Extensive and well-organized in vitro mineralization and crystallization of apatite were induced on the surface of dentin slices covered by CS nanospheres. All these features indicate that the porous CS nanospheres may be developed into a new intra-canal disinfectant-carrier for infected canal treatment.

Impact and interest:

2 citations in Scopus
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2 citations in Web of Science®

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ID Code: 50852
Item Type: Journal Article
Keywords: disinfectant, root canal treatment, nanosphere, controlled release, mineralization
DOI: 10.1016/j.matlet.2012.04.142
ISSN: 0167-577X
Subjects: Australian and New Zealand Standard Research Classification > BIOLOGICAL SCIENCES (060000)
Australian and New Zealand Standard Research Classification > ENGINEERING (090000) > BIOMEDICAL ENGINEERING (090300) > Biomaterials (090301)
Divisions: Current > Institutes > Institute of Health and Biomedical Innovation
Current > QUT Faculties and Divisions > Science & Engineering Faculty
Copyright Owner: Copyright 2012 Elsevier
Copyright Statement: This is the author’s version of a work that was accepted for publication in <Materials Letters>. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Materials Letters, [VOL 81, (2012)] DOI: 10.1016/j.matlet.2012.04.142
Deposited On: 13 Jun 2012 11:32
Last Modified: 12 Oct 2012 07:32

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