Porous Ca-Si-based nanospheres : a potential intra-canal disinfectant-carrier for infected canal treatment
Fan , Wei , Wu, Chengtie , Han , Pingping, Zhou, Yinghong, & Xiao, Yin (2012) Porous Ca-Si-based nanospheres : a potential intra-canal disinfectant-carrier for infected canal treatment. Materials Letters, 81, pp. 16-19.
The aim of this study is to develop a new intra-canal disinfectant-carrier for infected canal treatment. To achieve this purpose, a new porous Ca-Si (CS)-based nanosphere was synthesized and characterized. Results showed that the nanospheres can infiltrate into dentinal tubules and released the ampicillin over one week time in a sustained manner. The release of ampicillin from spheres has significantly antibacterial property. Extensive and well-organized in vitro mineralization and crystallization of apatite were induced on the surface of dentin slices covered by CS nanospheres. All these features indicate that the porous CS nanospheres may be developed into a new intra-canal disinfectant-carrier for infected canal treatment.
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|Item Type:||Journal Article|
|Keywords:||disinfectant, root canal treatment, nanosphere, controlled release, mineralization|
|Subjects:||Australian and New Zealand Standard Research Classification > BIOLOGICAL SCIENCES (060000)|
Australian and New Zealand Standard Research Classification > ENGINEERING (090000) > BIOMEDICAL ENGINEERING (090300) > Biomaterials (090301)
|Divisions:||Current > Institutes > Institute of Health and Biomedical Innovation|
Current > QUT Faculties and Divisions > Science & Engineering Faculty
|Copyright Owner:||Copyright 2012 Elsevier|
|Copyright Statement:||This is the author’s version of a work that was accepted for publication in <Materials Letters>. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Materials Letters, [VOL 81, (2012)] DOI: 10.1016/j.matlet.2012.04.142|
|Deposited On:||13 Jun 2012 11:32|
|Last Modified:||12 Oct 2012 07:32|
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