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Factors affecting 39K NMR detectability in rat tissue

Rashid, S. Abdul , Adam, W. R. , Craik, D. J. , Shehan, B. P. , & Wellard, R. Mark (1991) Factors affecting 39K NMR detectability in rat tissue. Magnetic Resonance in Medicine, 17(1), pp. 213-224.

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Abstract

In this study we have found that NMR detectability of 39K in rat thigh muscle may be substantially higher (up to 100% oftotal tissue potassium) than values previously reported of around 40%. The signal was found to consist of two superimposed components, one broad and one narrow, of approximately equal area. Investigations involving improvements in spectral parameters such as signal-to-noise ratio and baseline roll, together with computer simulations of spectra, show that the quality of the spectra has a major effect on the amount of signal detected, which is largely due to the loss of detectability of the broad signal component. In particular, lower-field spectrometers using conventional probes and detection methods generally have poorer signal-to-noise and worse baseline roll artifacts, which make detection of a broad component of the muscle signal difficult.

Impact and interest:

5 citations in Scopus
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8 citations in Web of Science®

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ID Code: 51356
Item Type: Journal Article
DOI: 10.1002/mrm.1910170124
ISSN: 1522-2594
Subjects: Australian and New Zealand Standard Research Classification > BIOLOGICAL SCIENCES (060000) > BIOCHEMISTRY AND CELL BIOLOGY (060100)
Australian and New Zealand Standard Research Classification > BIOLOGICAL SCIENCES (060000) > PHYSIOLOGY (060600)
Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > CLINICAL SCIENCES (110300) > Clinical Sciences not elsewhere classified (110399)
Divisions: Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > Institutes > Institute of Health and Biomedical Innovation
Current > QUT Faculties and Divisions > Science & Engineering Faculty
Copyright Owner: Copyright 1991 John Wiley & Sons, Inc.
Deposited On: 03 Jul 2012 10:28
Last Modified: 03 Jul 2012 10:28

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