Re-examining the evidence in radiation dermatitis management literature : an overview and a critical appraisal of systematic reviews
Chan, Raymond, Larsen, Emily , & Chan, Philip (2012) Re-examining the evidence in radiation dermatitis management literature : an overview and a critical appraisal of systematic reviews. International Journal of Radiation Oncology Biology Physics, 84(3), e357-e362.
To provide an overview and a critical appraisal of systematic reviews (SRs) of published interventions for the prevention/management of radiation dermatitis.
Methods and Materials:
We searched Medline, CINAHL, Embase, and the Cochrane Library. We also manually searched through individual reference lists of potentially eligible articles and a number of key journals in the topic area. Two authors screened all potential articles and included eligible SRs. Two authors critically appraised and extracted key findings from the included reviews using AMSTAR (the measurement tool for “assessment of multiple systematic reviews”).
Of 1837 potential titles, 6 SRs were included. A number of interventions have been reported to be potentially beneficial for managing radiation dermatitis. Interventions evaluated in these reviews included skin care advice, steroidal/nonsteroidal topical agents, systemic therapies, modes of radiation delivery, and dressings. However, all the included SRs reported that there is insufficient evidence supporting any single effective intervention. The methodological quality of the included studies varied, and methodological shortfalls in these reviews might create biases to the overall results or recommendations for clinical practice.
An up-to-date high-quality SR in the prevention/management of radiation dermatitis is needed to guide practice and direction for future research. We recommend that clinicians or guideline developers critically evaluate the information of SRs in their decision making.
Impact and interest:
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|Item Type:||Journal Article|
|Keywords:||Radiation Induced Skin Reactions, Radiation Dermatitis, Cancer Care, Overviews of systematic reviews, Critical Appraisal|
|Subjects:||Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > NURSING (111000) > Clinical Nursing - Secondary (Acute Care) (111003)|
Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > ONCOLOGY AND CARCINOGENESIS (111200) > Radiation Therapy (111208)
|Divisions:||Current > QUT Faculties and Divisions > Faculty of Health|
Current > Institutes > Institute of Health and Biomedical Innovation
Current > Schools > School of Nursing
|Copyright Owner:||Copyright 2012 Elsevier|
|Copyright Statement:||This is the author’s version of a work that was accepted for publication in International Journal of Radiation Oncology Biology Physics. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in International Journal of Radiation Oncology Biology Physics, [VOL 84, ISSUE 3, (2012)] DOI: 10.1016/j.ijrobp.2012.05.009|
|Deposited On:||09 Jul 2012 09:46|
|Last Modified:||03 Dec 2013 07:01|
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