Improved treatment of nicotine addiction and emerging pulmonary drug delivery

Islam, Nazrul & Rahman, Shafiqur (2012) Improved treatment of nicotine addiction and emerging pulmonary drug delivery. Drug Discoveries and Therapeutics, 6(3), pp. 123-132.

View at publisher (open access)


Nicotine addiction remains the leading cause of death and disease in developed and developing nations and a major cause of mortality around the world. Currently, nicotine replacement therapies (NRTs), bupropion, and varenicline are approved by the regulatory agencies as first-line treatments for nicotine addiction. Emerging evidence indicates that varenicline and bupropion have some therapeutic limitations for treating nicotine addiction with oral route of administration. Thus, continued investigation of innovative drug delivery for nicotine addiction remains a critical priority. This review will discuss some novel strategies and future directions for pulmonary drug delivery, an emerging route of administration for smoking cessation. It is anticipated that the advancement of knowledge on pulmonary drug delivery will provide better management for nicotine addiction and other addictive disorders.

Impact and interest:

5 citations in Scopus
Search Google Scholar™

Citation counts are sourced monthly from Scopus and Web of Science® citation databases.

These databases contain citations from different subsets of available publications and different time periods and thus the citation count from each is usually different. Some works are not in either database and no count is displayed. Scopus includes citations from articles published in 1996 onwards, and Web of Science® generally from 1980 onwards.

Citations counts from the Google Scholar™ indexing service can be viewed at the linked Google Scholar™ search.

Full-text downloads:

529 since deposited on 13 Sep 2012
35 in the past twelve months

Full-text downloads displays the total number of times this work’s files (e.g., a PDF) have been downloaded from QUT ePrints as well as the number of downloads in the previous 365 days. The count includes downloads for all files if a work has more than one.

ID Code: 53587
Item Type: Journal Article
Refereed: Yes
Keywords: Nicotine addiction, nicotinic receptor,, pulmonary drug delivery, dry powder inhaler, metered dose inhaler, nebulizer
DOI: 10.5582/ddt.2012.v6.3.123
ISSN: 1881-7831
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > PHARMACOLOGY AND PHARMACEUTICAL SCIENCES (111500) > Pharmacology and Pharmaceutical Sciences not elsewhere classified (111599)
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 2012 [Please consult the author]
Deposited On: 13 Sep 2012 23:05
Last Modified: 24 Jun 2017 20:41

Export: EndNote | Dublin Core | BibTeX

Repository Staff Only: item control page