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Improved treatment of nicotine addiction and emerging pulmonary drug delivery

Islam, Nazrul & Rahman, Shafiqur (2012) Improved treatment of nicotine addiction and emerging pulmonary drug delivery. Drug Discoveries and Therapeutics, 6(3), pp. 123-132.

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Abstract

Nicotine addiction remains the leading cause of death and disease in developed and developing nations and a major cause of mortality around the world. Currently, nicotine replacement therapies (NRTs), bupropion, and varenicline are approved by the regulatory agencies as first-line treatments for nicotine addiction. Emerging evidence indicates that varenicline and bupropion have some therapeutic limitations for treating nicotine addiction with oral route of administration. Thus, continued investigation of innovative drug delivery for nicotine addiction remains a critical priority. This review will discuss some novel strategies and future directions for pulmonary drug delivery, an emerging route of administration for smoking cessation. It is anticipated that the advancement of knowledge on pulmonary drug delivery will provide better management for nicotine addiction and other addictive disorders.

Impact and interest:

3 citations in Scopus
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ID Code: 53587
Item Type: Journal Article
Keywords: Nicotine addiction, nicotinic receptor, , pulmonary drug delivery, dry powder inhaler, metered dose inhaler, nebulizer
DOI: 10.5582/ddt.2012.v6.3.123
ISSN: 1881-7831
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > PHARMACOLOGY AND PHARMACEUTICAL SCIENCES (111500) > Pharmacology and Pharmaceutical Sciences not elsewhere classified (111599)
Divisions: Current > Schools > School of Clinical Sciences
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 2012 [Please consult the author]
Deposited On: 13 Sep 2012 23:05
Last Modified: 17 Sep 2012 10:24

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