Current status and future prospects for cultured limbal tissue transplants in Australia and New Zealand
Harkin, Damien G., Apel, Andrew , DiGirolamo, Nick , Watson, Stephanie , Brown, Karl , Daniell, Mark , McGhee, Jane , & McGhee, Charles N.J. (2013) Current status and future prospects for cultured limbal tissue transplants in Australia and New Zealand. Clinical And Experimental Ophthalmology, 41(3), pp. 272-281.
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Cultured limbal tissue transplants have become widely used over the last decade as a treatment for limbal stem cell deficiency (LSCD). While the number of patients afflicted with LSCD in Australia and New Zealand is considered to be relatively low, the impact of this disease on quality of life is so severe that the potential efficacy of cultured transplants has necessitated investigation. We presently review the basic biology and experimental strategies associated with the use of cultured limbal tissue transplants in Australia and New Zealand. In doing so, we aim to encourage informed discussion on the issues required to advance the use of cultured limbal transplants in Australia and New Zealand. Moreover, we propose that a collaborative network could be established to maintain access to the technology in conjunction with a number of other existing and emerging treatments for eye diseases.
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|Item Type:||Journal Article|
|Keywords:||Cornea, Limbus, Stem cells, Clinical trials, Australia, New Zealand, Corneal transpantation|
|Subjects:||Australian and New Zealand Standard Research Classification > TECHNOLOGY (100000) > MEDICAL BIOTECHNOLOGY (100400) > Regenerative Medicine (incl. Stem Cells and Tissue Engineering) (100404)|
Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300) > Ophthalmology (111301)
|Divisions:||Current > Schools > School of Biomedical Sciences|
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
|Copyright Owner:||Copyright 2012 The Author. Clinical and Experimental Ophthalmology Copyright 2012 Royal Australian and New Zealand College of Ophthalmologists.|
|Deposited On:||19 Sep 2012 10:18|
|Last Modified:||04 Dec 2013 13:15|
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