QUT ePrints

Current status and future prospects for cultured limbal tissue transplants in Australia and New Zealand

Harkin, Damien G., Apel, Andrew , DiGirolamo, Nick , Watson, Stephanie , Brown, Karl , Daniell, Mark , McGhee, Jane , & McGhee, Charles N.J. (2013) Current status and future prospects for cultured limbal tissue transplants in Australia and New Zealand. Clinical And Experimental Ophthalmology, 41(3), pp. 272-281.

[img] Accepted Version (PDF 4MB)
Administrators only until April 2014 | Request a copy from author

    View at publisher

    Abstract

    Cultured limbal tissue transplants have become widely used over the last decade as a treatment for limbal stem cell deficiency (LSCD). While the number of patients afflicted with LSCD in Australia and New Zealand is considered to be relatively low, the impact of this disease on quality of life is so severe that the potential efficacy of cultured transplants has necessitated investigation. We presently review the basic biology and experimental strategies associated with the use of cultured limbal tissue transplants in Australia and New Zealand. In doing so, we aim to encourage informed discussion on the issues required to advance the use of cultured limbal transplants in Australia and New Zealand. Moreover, we propose that a collaborative network could be established to maintain access to the technology in conjunction with a number of other existing and emerging treatments for eye diseases.

    Impact and interest:

    1 citations in Scopus
    Search Google Scholar™
    0 citations in Web of Science®

    Citation countsare sourced monthly from Scopus and Web of Science® citation databases.

    These databases contain citations from different subsets of available publications and different time periods and thus the citation count from each is usually different. Some works are not in either database and no count is displayed. Scopus includes citations from articles published in 1996 onwards, and Web of Science® generally from 1980 onwards.

    Citations counts from the Google Scholar™ indexing service can be viewed at the linked Google Scholar™ search.

    ID Code: 53728
    Item Type: Journal Article
    Keywords: Cornea, Limbus, Stem cells, Clinical trials, Australia, New Zealand, Corneal transpantation
    DOI: 10.1111/j.1442-9071.2012.02877.x
    ISSN: 1442-9071
    Subjects: Australian and New Zealand Standard Research Classification > TECHNOLOGY (100000) > MEDICAL BIOTECHNOLOGY (100400) > Regenerative Medicine (incl. Stem Cells and Tissue Engineering) (100404)
    Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300) > Ophthalmology (111301)
    Divisions: Current > Schools > School of Biomedical Sciences
    Current > QUT Faculties and Divisions > Faculty of Health
    Current > Institutes > Institute of Health and Biomedical Innovation
    Copyright Owner: Copyright 2012 The Author. Clinical and Experimental Ophthalmology Copyright 2012 Royal Australian and New Zealand College of Ophthalmologists.
    Deposited On: 19 Sep 2012 10:18
    Last Modified: 04 Dec 2013 13:15

    Export: EndNote | Dublin Core | BibTeX

    Repository Staff Only: item control page