Wolbachia-mediated resistance to dengue virus infection and death at the cellular level
Frentiu, F.D., Robinson, J. , Young, P.R. , McGraw, E.A. , & O'Neill, S.L. (2010) Wolbachia-mediated resistance to dengue virus infection and death at the cellular level. PLoS One, 5(10), e13398.
Dengue is currently the most important arthropod-borne viral disease of humans. Recent work has shown dengue virus displays limited replication in its primary vector, the mosquito Aedes aegypti, when the insect harbors the endosymbiotic bacterium Wolbachia pipientis. Wolbachia-mediated inhibition of virus replication may lead to novel methods of arboviral control, yet the functional and cellular mechanisms that underpin it are unknown.
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|Item Type:||Journal Article|
|Keywords:||Wolbachia pipientis, dengue virus, viral interference|
|Subjects:||Australian and New Zealand Standard Research Classification > BIOLOGICAL SCIENCES (060000)|
Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000)
|Divisions:||Current > QUT Faculties and Divisions > Faculty of Health|
Current > Institutes > Institute of Health and Biomedical Innovation
|Deposited On:||12 Oct 2012 10:44|
|Last Modified:||16 Sep 2013 17:00|
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