Advances and future directions for management of trauma patients with musculoskeletal injuries

Balogh, Zsolt J, Reumann, Marie K, Gruen, Russell L, Mayer-Kuckuk, Philipp, Schuetz, Michael A, Harris, Ian A, Gabbe, Belinda J, & Bhandari, Mohit (2012) Advances and future directions for management of trauma patients with musculoskeletal injuries. The Lancet, 380(9847), pp. 1109-1119.

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Musculoskeletal injuries are the most common reason for operative procedures in severely injured patients and are major determinants of functional outcomes. In this paper, we summarise advances and future directions for management of multiply injured patients with major musculoskeletal trauma. Improved understanding of fracture healing has created new possibilities for management of particularly challenging problems, such as delayed union and non union of fractures and large bone defects. Optimum timing of major orthopaedic interventions is guided by increased knowledge about the immune response after injury. Individual treatment should be guided by trading off the benefits of early definitive skeletal stabilisation, and the potentially life-threatening risks of systemic complications such as fat embolism, acute lung injury, and multiple organ failure. New methods for measurement of fracture healing and function and quality of life outcomes pave the way for landmark trials that will guide the future management of musculoskeletal injuries.

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38 citations in Scopus
32 citations in Web of Science®
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ID Code: 54589
Item Type: Journal Article
Refereed: Yes
Keywords: trauma, musculoskeletal injury, trauma management
DOI: 10.1016/S0140-6736(12)60991-X
ISSN: 0140-6736
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000)
Divisions: Current > Institutes > Institute of Health and Biomedical Innovation
Current > QUT Faculties and Divisions > Science & Engineering Faculty
Copyright Owner: Copyright 2012 Elsevier Ltd.
Deposited On: 07 Nov 2012 00:35
Last Modified: 17 Jul 2017 00:01

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