Plant-produced vaccines: promise and reality

Rybicki, E. P. (2009) Plant-produced vaccines: promise and reality. Drug Discovery Today, 14(1-2), pp. 16-24.

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Plant-produced vaccines are a much-hyped development of the past two decades, whose time to embrace reality may have finally come. Vaccines have been developed against viral, bacterial, parasite and allergenic antigens, for humans and for animals; a wide variety of plants have been used for stable transgenic expression as well as for transient expression via Agrobacterium tumefaciens and plant viral vectors. A great many products have shown significant immunogenicity; several have shown efficacy in target animals or in animal models. The realised potential of plant-produced vaccines is discussed, together with future prospects for production and registration. © 2008 Elsevier Ltd. All rights reserved.

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90 citations in Web of Science®

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ID Code: 54926
Item Type: Journal Article
Refereed: Yes
Additional Information: Cited By (since 1996): 52
Export Date: 12 November 2012
Source: Scopus
DOI: 10.1016/j.drudis.2008.10.002
Deposited On: 20 Nov 2012 02:46
Last Modified: 20 Nov 2012 02:57

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