Dating the origins of the maize-adapted strain of maize streak virus, MSV-A

Harkins, G. W., Martin, D. P., Duffy, S., Monjane, A. L., Shepherd, D. N., Windram, O. P., Owor, B. E., Donaldson, L., van Antwerpen, T., Sayed, R. A., Flett, B., Ramusi, M., Rybicki, E. P., Peterschmitt, M., & Varsani, A. (2009) Dating the origins of the maize-adapted strain of maize streak virus, MSV-A. Journal of General Virology, 90(12), pp. 3066-3074.

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Maize streak virus (MSV), which causes maize streak disease (MSD), is one of the most serious biotic threats to African food security. Here, we use whole MSV genomes sampled over 30 years to estimate the dates of key evolutionary events in the 500 year association of MSV and maize. The substitution rates implied by our analyses agree closely with those estimated previously in controlled MSV evolution experiments, and we use them to infer the date when the maize-adapted strain, MSV-A, was generated by recombination between two grass-adapted MSV strains. Our results indicate that this recombination event occurred in the mid-1800s, ∼20 years before the first credible reports of MSD in South Africa and centuries after the introduction of maize to the continent in the early 1500s. This suggests a causal link between MSV recombination and the emergence of MSV-A as a serious pathogen of maize. © 2009 SGM.

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25 citations in Scopus
25 citations in Web of Science®
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ID Code: 54955
Item Type: Journal Article
Refereed: Yes
Additional Information: Cited By (since 1996): 12
Export Date: 12 November 2012
Source: Scopus
DOI: 10.1099/vir.0.015537-0
Deposited On: 20 Nov 2012 02:46
Last Modified: 29 May 2013 16:53

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