Riding the tide of biopharming in Africa: Considerations for risk assessment

Chakauya, E., Chikwamba, R., & Rybicki, E. P. (2006) Riding the tide of biopharming in Africa: Considerations for risk assessment. South African Journal of Science, 102(7-8), pp. 284-288.

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In the past few years, plant biotechnology has gone beyond traditional agricultural production of food, feed and fibre, and moved to address more complex contemporary health, social and industrial challenges. The new era involves production of novel pharmaceutical products, speciality and fine chemicals, phytoremediation and production of renewable energy resources to replace non-renewable fossil fuels. Plants have been shown to provide a genuine and low-cost alternative production system for high-value products. Currently, the principal plant-made products include antibodies, feed additives, vaccine antigens and hormones for human and animal health, and industrial proteins. Despite the unique advantages of scalability, cost and product safety, issues of politics, environmental impact, regulation and socioeconomics still limit the adoption of biopharmaceuticals, especially in the developing world. Plant-based production systems have further complicated biosafety, gene flow and environmental impact assessments with generally genetically modified plants, topics that are already partially understood. This article provides a background to biopharming, highlighting basic considerations for risk assessment and regulation in developing countries, with an emphasis on plant-based vaccine production in South Africa.

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6 citations in Scopus
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4 citations in Web of Science®

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ID Code: 54978
Item Type: Journal Article
Refereed: Yes
Additional Information: Cited By (since 1996): 6 Export Date: 12 November 2012 Source: Scopus
Deposited On: 20 Nov 2012 02:46
Last Modified: 20 Nov 2012 02:57

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