QUT ePrints

Why participate in an Alzheimer’s disease clinical trial? Is it of benefit to carers and patients?

Mastwyk, Maree, Macfarlane, Stephen, LoGiudice, Dina, & Sullivan, Karen A. (2003) Why participate in an Alzheimer’s disease clinical trial? Is it of benefit to carers and patients? International Psychogeriatrics, 15(2), pp. 149-156.

View at publisher

Abstract

Background: We explored carer motivation for seeking participation for a relative in an Alzheimer’s disease (AD) clinical drug trial, to assess impressions of the value of trial participation. We also surveyed the carers of patients who did not meet study-entry screening criteria to see if our conduct of the screening visit was acceptable and ethical. Method: A retrospective questionnaire was sent to the carers of 36 randomised participants and 22 carers of patients who did not meet study entry screening criteria for an AD clinical treatment trial. Results: Twenty-nine (81%) of the trial participant carers and 15 (68%) of carers of the group who did not meet study entry criteria, returned their questionnaires, with sufficient information for analysis. The prime motivators in seeking trial participation were: to help their relative feel better and live longer, to contribute to medical science, to improve the health of others and the hope of a cure. Carers of both groups found research staff supportive and would recommend trial participation to others. Conclusions: Even though trial participation is onerous and patients were generally perceived by carers as not having improved, both the screening visit and participation in the trial itself were seen as positive experiences and the expectations of carers were met.

Impact and interest:

7 citations in Scopus
Search Google Scholar™
10 citations in Web of Science®

Citation countsare sourced monthly from Scopus and Web of Science® citation databases.

These databases contain citations from different subsets of available publications and different time periods and thus the citation count from each is usually different. Some works are not in either database and no count is displayed. Scopus includes citations from articles published in 1996 onwards, and Web of Science® generally from 1980 onwards.

Citations counts from the Google Scholar™ indexing service can be viewed at the linked Google Scholar™ search.

Full-text downloads:

118 since deposited on 23 Nov 2006
7 in the past twelve months

Full-text downloadsdisplays the total number of times this work’s files (e.g., a PDF) have been downloaded from QUT ePrints as well as the number of downloads in the previous 365 days. The count includes downloads for all files if a work has more than one.

ID Code: 5540
Item Type: Journal Article
Keywords: Sullivan, Alzheimers disease, caregivers, clinical trials
DOI: 10.1017/S1041610203008834
ISSN: 1041-6102
Subjects: Australian and New Zealand Standard Research Classification > PSYCHOLOGY AND COGNITIVE SCIENCES (170000) > PSYCHOLOGY (170100) > Health Clinical and Counselling Psychology (170106)
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 2003 Cambridge University Press
Copyright Statement: Reproduced in accordance with the copyright policy of the publisher.
Deposited On: 23 Nov 2006
Last Modified: 29 Feb 2012 22:58

Export: EndNote | Dublin Core | BibTeX

Repository Staff Only: item control page