Nano- to macroscale remodeling of functional tissue-engineered bone

Woodruff, Maria A., Lange, Claudia, Chen, Fulin, Fratzl, Peter, & Hutmacher, Dietmar (2013) Nano- to macroscale remodeling of functional tissue-engineered bone. Advanced Healthcare Materials, 2(4), pp. 546-551.

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Abstract

A higher degree of mineralization is found within scaffold groups implanted with cells compared to scaffold alone demonstrating greater bone regenerative potential of cell-scaffold constructs Tissue engineered bone analysed using ESEM and SAXS demonstrates bone formation within the scaffold to be preferentially aligned around the scaffold struts. The mineral particles are not shown to orientate around the osteons within the native bone.

Impact and interest:

4 citations in Scopus
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4 citations in Web of Science®

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250 since deposited on 12 Dec 2012
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ID Code: 55501
Item Type: Journal Article
Refereed: Yes
Keywords: bone, tissue engineering, scaffold
DOI: 10.1002/adhm.201200289
ISSN: 2192-2640
Subjects: Australian and New Zealand Standard Research Classification > ENGINEERING (090000) > BIOMEDICAL ENGINEERING (090300)
Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > CLINICAL SCIENCES (110300) > Orthopaedics (110314)
Divisions: Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > Institutes > Institute of Health and Biomedical Innovation
Current > QUT Faculties and Divisions > Science & Engineering Faculty
Funding:
Copyright Owner: Copyright 2012 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Deposited On: 12 Dec 2012 02:13
Last Modified: 03 Sep 2016 11:35

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