Comparison of robust criteria for D-optimal design
Foo, Lee Kien, McGree, James, Eccleston, John, & Duffull, Stephen (2012) Comparison of robust criteria for D-optimal design. Journal of Biopharmaceutical Statistics, 22(6), pp. 1193-1205.
This study compared the performance of a local and three robust optimality criteria in terms of the standard error for a one-parameter and a two-parameter nonlinear model with uncertainty in the parameter values. The designs were also compared in conditions where there was misspecification in the prior parameter distribution. The impact of different correlation between parameters on the optimal design was examined in the two-parameter model. The designs and standard errors were solved analytically whenever possible and numerically otherwise.
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|Item Type:||Journal Article|
|Keywords:||D-optimal design, ED-design, Nonlinear model, Pharmacokinetics, Robust design, Standard error|
|Subjects:||Australian and New Zealand Standard Research Classification > MATHEMATICAL SCIENCES (010000) > STATISTICS (010400)|
|Divisions:||Current > QUT Faculties and Divisions > Science & Engineering Faculty|
|Deposited On:||03 Jan 2013 05:55|
|Last Modified:||12 Jun 2013 15:25|
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