The role of Ureaplasma urealyticum in adverse pregnancy outcome

Knox, Christine L., Cave, Donald, Farrell, David, Eastment, Henry, & Timms, Peter (1997) The role of Ureaplasma urealyticum in adverse pregnancy outcome. Australian and New Zealand Journal of Obstetrics and Gynaecology, 37(1), pp. 45-51.

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We investigated Ureaplasma urealyticum genital tract colonisation rates in an Australian population to determine whether colonisation was associated with adverse pregnancy outcome. Women attending an antenatal clinic were evaluated for lower genital tract colonisation at their first antenatal visit (162 women) and at 28 weeks gestation (120 women). Placentas from 92 women were cultured. U. urealyticum was the predominant isolate from the lower (57.4%) and upper (17.4%) genital tract in this population of pregnant women. U. urealyticum was a persistent coloniser during mid-trimester of pregnancy (in 88% of women colonised) whereas M. hominis, G. vaginalis, and Group B streptococcus were present as transient flora of the lower genital tract. Lower genital tract colonisation during pregnancy was not directly associated with adverse pregnancy outcome. However preterm delivery in afebrile, asymptomatic women, could possibly be associated with chorioamnionitis (four of 16 preterm births). Screening of women with a history of preterm birth may prevent upper genital tract infections and preterm delivery.

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ID Code: 56088
Item Type: Journal Article
Refereed: Yes
Keywords: Ureaplasma urealyticum, pregnancy outcome, preterm delivery, chorioamnionitis
DOI: 10.1111/j.1479-828X.1997.tb02216.x
ISSN: 0004-8666
Subjects: Australian and New Zealand Standard Research Classification > BIOLOGICAL SCIENCES (060000) > MICROBIOLOGY (060500) > Infectious Agents (060502)
Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > PAEDIATRICS AND REPRODUCTIVE MEDICINE (111400) > Reproduction (111404)
Divisions: Current > Schools > School of Biomedical Sciences
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 1997 Wiley-Blackwell Publishing Asia
Deposited On: 04 Jan 2013 01:50
Last Modified: 04 Jan 2013 01:53

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