Numerical simulation of red blood cells' deformation using SPH method

Polwaththe-Gallage, Hasitha-Nayanajith, Gu, YuanTong, Saha, Suvash C., Senadeera, Wijitha, & Oloyede, Adekunle (2012) Numerical simulation of red blood cells' deformation using SPH method. In Gu, YuanTong & Saha, Suvash C. (Eds.) 4th International Conference on Computational Methods (ICCM 2012), 25-28 November 2012, Crowne Plaza, Gold Coast, QLD.

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A numerical simulation method for the Red Blood Cells’ (RBC) deformation is presented in this study. The two-dimensional RBC membrane is modeled by the spring network, where the elastic stretch/compression energy and the bending energy are considered with the constraint of constant RBC surface area. Smoothed Particle Hydrodynamics (SPH) method is used to solve the Navier-Stokes equation coupled with the Plasma-RBC membrane and Cytoplasm- RBC membrane interaction. To verify the method, the motion of a single RBC is simulated in Poiseuille flow and compared with the results reported earlier. Typical motion and deformation mechanism of the RBC is observed.

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ID Code: 56948
Item Type: Conference Paper
Refereed: Yes
Keywords: Red Blood Cell (RBC), Smoothed Particle Hydrodynamics (SPH), Particle Methods, Meshfree Methods, Erythrocytes
Subjects: Australian and New Zealand Standard Research Classification > ENGINEERING (090000) > BIOMEDICAL ENGINEERING (090300) > Biomechanical Engineering (090302)
Australian and New Zealand Standard Research Classification > ENGINEERING (090000) > MECHANICAL ENGINEERING (091300) > Numerical Modelling and Mechanical Characterisation (091307)
Divisions: Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > QUT Faculties and Divisions > Science & Engineering Faculty
Copyright Owner: Copyright 2012 (please consult the authors).
Deposited On: 07 Feb 2013 06:40
Last Modified: 13 Jan 2014 05:39

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