Numerical simulation of red blood cells’ motion : a review

Polwaththe-Gallage, Hasitha-Nayanajith, Gu, YuanTong, Saha, Suvash C., Senadeera, Wijitha, & Oloyede, Adekunle (2012) Numerical simulation of red blood cells’ motion : a review. In Gu, YuanTong & Saha, Suvash C. (Eds.) 4th International Conference on Computational Methods (ICCM 2012), 25-28 November 2012, Crowne Plaza, Gold Coast, QLD.

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Abstract

The micro-circulation of blood plays an important role in human body by providing oxygen and nutrients to the cells and removing carbon dioxide and wastes from the cells. This process is greatly affected by the rheological properties of the Red Blood Cells (RBCs). Changes in the rheological properties of the RBCs are caused by certain human diseases such as malaria and sickle cell diseases. Therefore it is important to understand the motion and deformation mechanism of RBCs in order to diagnose and treat this kind of diseases. Although, many methods have been developed to explore the behavior of the RBCs in micro-channels, they could not explain the deformation mechanism of the RBCs properly. Recently developed Particle Methods are employed to explain the RBCs’ behavior in micro-channels more comprehensively. The main objective of this study is to critically analyze the present methods, used to model the RBC behavior in micro-channels, in order to develop a computationally efficient particle based model to describe the complete behavior of the RBCs in micro-channels accurately and comprehensively

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ID Code: 56983
Item Type: Conference Paper
Refereed: Yes
Keywords: Red Blood Cells, RBCs, Erythrocytes, Microcirculation, Numerical Simulations, Biomechanical, Mathematical Modelling
Subjects: Australian and New Zealand Standard Research Classification > ENGINEERING (090000) > BIOMEDICAL ENGINEERING (090300) > Biomechanical Engineering (090302)
Australian and New Zealand Standard Research Classification > ENGINEERING (090000) > MECHANICAL ENGINEERING (091300) > Numerical Modelling and Mechanical Characterisation (091307)
Divisions: Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > QUT Faculties and Divisions > Science & Engineering Faculty
Copyright Owner: Copyright 2012 (please consult the authors).
Deposited On: 08 Feb 2013 05:44
Last Modified: 14 Jan 2014 08:35

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