The influence of antioxidant supplementation on markers of inflammation and the relationship to oxidative stress after exercise

Peake, Jonathan, Suzuki, Katsuhiko, & Coombes, Jeff S. (2007) The influence of antioxidant supplementation on markers of inflammation and the relationship to oxidative stress after exercise. Journal of Nutritional Biochemistry, 18(6), pp. 357-371.

View at publisher


Interest in the relationship between inflammation and oxidative stress has increased dramatically in recent years, not only within the clinical setting but also in the fields of exercise biochemistry and immunology. Inflammation and oxidative stress share a common role in the etiology of a variety of chronic diseases. During exercise, inflammation and oxidative stress are linked via muscle metabolism and muscle damage. Because oxidative stress and inflammation have traditionally been associated with fatigue and impaired recovery from exercise, research has focused on nutritional strategies aimed at reducing these effects. In this review, we have evaluated the findings of studies involving antioxidant supplementation on alterations in markers of inflammation (e.g., cytokines, C-reactive protein and cortisol). This review focuses predominantly on the role of reactive oxygen and nitrogen species generated from muscle metabolism and muscle damage during exercise and on the modulatory effects of antioxidant supplements. Furthermore, we have analyzed the influence of factors such as the dose, timing, supplementation period and bioavailability of antioxidant nutrients.

Impact and interest:

72 citations in Scopus
Search Google Scholar™
64 citations in Web of Science®

Citation counts are sourced monthly from Scopus and Web of Science® citation databases.

These databases contain citations from different subsets of available publications and different time periods and thus the citation count from each is usually different. Some works are not in either database and no count is displayed. Scopus includes citations from articles published in 1996 onwards, and Web of Science® generally from 1980 onwards.

Citations counts from the Google Scholar™ indexing service can be viewed at the linked Google Scholar™ search.

ID Code: 59894
Item Type: Journal Article
Refereed: Yes
DOI: 10.1016/j.jnutbio.2006.10.005
ISSN: 0955-2863
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > HUMAN MOVEMENT AND SPORTS SCIENCE (110600) > Exercise Physiology (110602)
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Deposited On: 13 May 2013 00:41
Last Modified: 26 Jul 2013 05:38

Export: EndNote | Dublin Core | BibTeX

Repository Staff Only: item control page