The willingness of women to participate in a long-term trial of hormone replacement therapy : A qualitative study using focus groups.
Hepworth, J, Paine, B, Miles, H, Marley, J, & MacLennan, A (2002) The willingness of women to participate in a long-term trial of hormone replacement therapy : A qualitative study using focus groups. Psychology, Health & Medicine, 7(4), pp. 469-476.
The actual proportion of eligible people who participate in clinical trials is low. Consequently, a qualitative study of the willingness of women who are postmenopausal to participate in a long-term randomized control trial of hormone replacement therapy (HRT) designed to investigate the prevention of degenerative diseases was conducted. Focus group methodology was employed to explore the personal and social aspects of decision making about trial participation. Participants were randomly selected from the patient age-sex registers of four University of Adelaide general practices. Twenty-one women participated in four focus groups. The reasons for and against trial participation were examined using qualitative content analysis; ( n = 18) women were unwilling to participate in the trial. The lack of perceived individual benefit, minimal altruism, the risk of breast cancer and side effects, not wanting to take unnecessary medication, a ten-year commitment, and negative experiences of HRT use, were the main reasons given for not entering the trial. Of the few women ( n = 3) who clearly would enter the trial, free prescriptions and a positive history of using HRT were the main reasons for participation. The perceived disadvantages of clinical trials of HRT deter women from participating in a long-term clinical trial of HRT. An investment in education and information to eligible participants about both the risks and potential benefits of HRT may improve trial recruitment.
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|Item Type:||Journal Article|
|Divisions:||Current > QUT Faculties and Divisions > Faculty of Health
Current > Schools > School of Public Health & Social Work
|Copyright Owner:||Taylor & Francis|
|Copyright Statement:||Copyright Taylor & Francis|
|Deposited On:||03 Jun 2013 09:24|
|Last Modified:||03 Jun 2013 09:24|
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