Biomechanics of synthetic elastin : insights from Magnetic Resonance microimaging

Momot, Konstantin I., Powell, Sean K., Mithieux, Suzanne M. , & Weiss, Anthony S. (2013) Biomechanics of synthetic elastin : insights from Magnetic Resonance microimaging. Advanced Materials Research, 699, pp. 457-463.

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We used Magnetic Resonance microimaging (μMRI) to study the compressive behaviour of synthetic elastin. Compression-induced changes in the elastin sample were quantified using longitudinal and transverse spin relaxation rates (R1 and R2, respectively). Spatially-resolved maps of each spin relaxation rate were obtained, allowing the heterogeneous texture of the sample to be observed with and without compression. Compression resulted in an increase of both the mean R1 and the mean R2, but most of this increase was due to sub-locations that exhibited relatively low R1 and R2 in the uncompressed state. This behaviour can be described by differential compression, where local domains in the hydrogel with a relatively low biopolymer content compress more than those with a relatively high biopolymer content.

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ID Code: 60637
Item Type: Journal Article
Refereed: Yes
Additional Information: Edited by Jin Yun and Dehuai Zeng
Keywords: Tropoelastin, biomaterials, magnetic resonance imaging, spin relaxation, biomechanics of soft tissues, elasticity, entropic model of biopolymer deformation
DOI: 10.4028/
ISSN: 1662-8985
Subjects: Australian and New Zealand Standard Research Classification > PHYSICAL SCIENCES (020000) > OTHER PHYSICAL SCIENCES (029900) > Biological Physics (029901)
Divisions: Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > QUT Faculties and Divisions > Science & Engineering Faculty
Copyright Owner: Copyright 2013 Trans Tech Publications, Switzerland
Deposited On: 07 Jun 2013 04:11
Last Modified: 19 Jan 2014 12:55

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