In vitro models for investigating keratinocyte responses to ultraviolet B radiation

Fernandez, Tara L. (2013) In vitro models for investigating keratinocyte responses to ultraviolet B radiation. PhD thesis, Queensland University of Technology.

Abstract

This thesis describes the use of 2- and 3-dimensional cell-based models for studying how skin cells respond to ultraviolet radiation. These methods were used to investigate skin damage and repair after exposure to radiation in the context of skin cancer development. Interactions between different skin cell types were demonstrated as being significant in protecting against ultraviolet radiation-induced skin damage. This has important implications in understanding how skin cancers occur, as well as in the development of new strategies to prevent and treat them.

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682 since deposited on 26 Jul 2013
139 in the past twelve months

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ID Code: 61515
Item Type: QUT Thesis (PhD)
Supervisor: Upton, Zee, Kimlin, Michael, Dawson, Rebecca, Van Lonkhuyzen, Derek, & Leavesley, David
Keywords: skin, photobiology, keratinocytes, ultraviolet radiation, skin cancer, skin equivalent, in vitro models, sun exposure
Divisions: Current > Schools > School of Biomedical Sciences
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Institution: Queensland University of Technology
Deposited On: 26 Jul 2013 07:25
Last Modified: 08 Sep 2015 02:49

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