Genetics of menstrual migraine : the molecular evidence

Colson, Natalie, Fernandez, Francesca, & Griffiths, Lyn R. (2010) Genetics of menstrual migraine : the molecular evidence. Current Pain and Headache Reports, 14(5), pp. 389-395.

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Abstract

Migraine is considered to be a multifactorial disorder in which genetic, environmental, and, in the case of menstrual and menstrually related migraine, hormonal events influence the phenotype. Certainly, the role of female sex hormones in migraine has been well established, yet the mechanism behind this well-known relationship remains unclear. This review focuses on the potential role of hormonally related genes in migraine, summarizes results of candidate gene studies to date, and discusses challenges and issues involved in interpreting hormone-related gene results. In light of the molecular evidence presented, we discuss future approaches for analysis with the view to elucidate the complex genetic architecture that underlies the disorder.

Impact and interest:

5 citations in Scopus
7 citations in Web of Science®
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ID Code: 62631
Item Type: Journal Article
Refereed: No
DOI: 10.1007/s11916-010-0129-3
ISSN: 1534-3081
Divisions: Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 2010 Springer Healthcare
Deposited On: 18 Sep 2013 03:28
Last Modified: 01 Nov 2013 01:39

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