The role of vascular and hormonal genes in migraine susceptibility

Colson, Natalie J., Lea, Rod A., Quinlan, Sharon, & Griffiths, Lyn R. (2006) The role of vascular and hormonal genes in migraine susceptibility. Molecular Genetics and Metabolism, 88(2), pp. 107-113.

View at publisher


Migraine is a primary headache disorder that involves both genetic and environmental components. Migraine is considered to be a polygenic disorder with a number of susceptibility genes having a minor but nonetheless significant impact on susceptibility. Migraine candidate gene studies have concentrated mainly on genes involved in neurotransmitter pathways, however evidence also exists for a role for alterations in vascular and hormonal function in migraine susceptibility. We present here a mini-review of genetic studies, investigating the potential role of vascular and hormonal gene variants, and discuss how vascular and hormonal dysfunction may impact on migraine susceptibility. We propose that the potential role of vascular and hormonal genes in this disorder warrants further investigation.

Impact and interest:

25 citations in Scopus
Search Google Scholar™
24 citations in Web of Science®

Citation counts are sourced monthly from Scopus and Web of Science® citation databases.

These databases contain citations from different subsets of available publications and different time periods and thus the citation count from each is usually different. Some works are not in either database and no count is displayed. Scopus includes citations from articles published in 1996 onwards, and Web of Science® generally from 1980 onwards.

Citations counts from the Google Scholar™ indexing service can be viewed at the linked Google Scholar™ search.

ID Code: 62719
Item Type: Journal Article
Refereed: Yes
DOI: 10.1016/j.ymgme.2005.11.013
ISSN: 10967192
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 2006 Academic Press
Deposited On: 20 Sep 2013 02:08
Last Modified: 02 Jul 2014 23:00

Export: EndNote | Dublin Core | BibTeX

Repository Staff Only: item control page