Comparison of diagnostic tests in myasthenia gravis

Nicholson, G. A., McLeod, J. G., & Griffiths, Lyn R. (1983) Comparison of diagnostic tests in myasthenia gravis. Clinical and Experimental Neurology, 19, pp. 45-49.

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Results of 3 tests, intravenous edrophonium chloride, EMG, and acetylcholine receptor antibody testing, were compared in patients with generalised and ocular myasthenia gravis. None of the 3 tests was positive in any patient with a diagnosis other than myasthenia. However, equivocal results were obtained with edrophonium and EMG testing in some patients with myasthenia gravis and in patients with other diseases. It is concluded from this survey that antibody and edrophonium testing were equally efficient in detecting generalised myasthenia gravis. Edrophonium testing was superior in ocular myasthenia gravis. Although the yields from each test varied, all 3 tests were needed for the evaluation of some myasthenia gravis patients as each test may provide additional information.

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ID Code: 63150
Item Type: Journal Article
Refereed: No
Additional Information: 6568927
Keywords: autoantibody, cholinergic receptor, diagnostic agent, edrophonium, article, comparative study, electromyography, extraocular muscle, human, immunology, myasthenia gravis, Autoantibodies, Comparative Study, Edrophonium, Electromyography, Human, Myasthenia Gravis, Oculomotor Muscles, Receptors, Cholinergic
ISSN: 0196-6383
Divisions: Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 1983 Adis Press Australasia
Deposited On: 08 Oct 2013 00:38
Last Modified: 08 Oct 2013 00:38

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