Quality of life, fatigue and activity in Australians with chronic kidney disease : a longitudinal study

Bonner, Ann, Caltabiano, Marie, & Berlund, Lois (2013) Quality of life, fatigue and activity in Australians with chronic kidney disease : a longitudinal study. Nursing & Health Sciences, 15(3), pp. 360-367.

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Aims and objectives

This study sought to determine the relationship between health related quality of life (HRQoL), fatigue and activity levels of people with anaemia secondary to chronic kidney disease (CKD) over a 12 month period following the introduction of an erythropoietin stimulating agent (ESA).


CKD occurs in five stages and it is a complex chronic illness which severely impacts on an individual’s HRQoL, and ability to perform everyday activities. Fatigue is also a common symptom experienced by people with CKD.

Design and methods

Using a longitudinal repeated measures design, 28 people with CKD completed the SF-36, human activity profile and fatigue severity scale at the commencement of an ESA and then at 3, 6 and 12 months.


Over a 12 month period, people reported a significant change in HRQoL in relation to role physical, vitality, mental health/emotional well-being and overall mental health. However activity levels did not significantly improve during that time. Both the amount of breathlessness and level of fatigue were highest at baseline and declined over time. Both fatigue and breathlessness were correlated with less reported general health over time.


Renal nurses, in dialysis units and CKD outpatient clinics, have repeated and frequent contact with people with CKD over long periods of time, and are in an ideal position to routinely assess fatigue and activity levels and to institute timely interventions. Early detection would enable timely nursing interventions to optimise HRQoL and independent activity.

Relevance to Clinical Practice

Drawing on rehabilitation nursing interventions could assist renal nurses to minimize the burden of fatigue and its impact on simple everyday activities and a person’s quality of life. These interventions are important for people who are living at home and could assist in lowering the burden on home support services.

Impact and interest:

12 citations in Scopus
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11 citations in Web of Science®

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ID Code: 63340
Item Type: Journal Article
Refereed: Yes
Keywords: Renal failure, Everyday life, Fatigue, Renal nursing, Chronic illness, Australia
DOI: 10.1111/nhs.12038
ISSN: 1442-2018
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > NURSING (111000)
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Current > Schools > School of Nursing
Copyright Owner: Copyright 2013 Wiley Publishing Asia Pty Ltd
Deposited On: 14 Oct 2013 23:47
Last Modified: 02 Oct 2014 09:23

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