Spatial Tumor-Immune Modeling
In this paper, we carry out an examination of four mechanisms that can potentially lead to changing morphologies in a growing tumor: variations in nutrient consumption rates, cellular adhesion, excessive consumption of nutrients by tumor cells and immune cell interactions with the tumor. We present numerical simulations using a hybrid PDE-cellular automata (CA) model demonstrating the effects of each mechanism before discussing hypotheses about the contribution of each mechanism to morphology change.
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|Item Type:||Journal Article|
|Additional Information:||For more information please refer to the publisher's website (link above) or contact the author: firstname.lastname@example.org|
|Keywords:||Tumor, Immune, Cellular automata, Cellular adhesion, Tumor morphology|
|Subjects:||Australian and New Zealand Standard Research Classification > MATHEMATICAL SCIENCES (010000) > APPLIED MATHEMATICS (010200) > Biological Mathematics (010202)|
Australian and New Zealand Standard Research Classification > MATHEMATICAL SCIENCES (010000)
Australian and New Zealand Standard Research Classification > MATHEMATICAL SCIENCES (010000) > OTHER MATHEMATICAL SCIENCES (019900)
|Divisions:||Past > QUT Faculties & Divisions > Faculty of Science and Technology|
|Copyright Owner:||Copyright 2006 Taylor & Francis|
|Copyright Statement:||First published in Computational and Mathematical Methods in Medicine 7(2-3):pp. 159-176.|
|Deposited On:||09 Mar 2007|
|Last Modified:||29 Feb 2012 23:21|
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