Improving in vivo models of fracture fixation associated osteomyelitis

Calabro, Lorenzo (2013) Improving in vivo models of fracture fixation associated osteomyelitis. Masters by Research thesis, Queensland University of Technology.


This project’s aim was to create new experimental models in small animals for the investigation of infections related to bone fracture fixation implants. Animal models are essential in orthopaedic trauma research and this study evaluated new implants and surgical techniques designed to improve standardisation in these experiments, and ultimately to minimise the number of animals needed in future work. This study developed and assessed procedures using plates and inter-locked nails to stabilise fractures in rabbit thigh bones. Fracture healing was examined with mechanical testing and histology. The results of this work contribute to improvements in future small animal infection experiments.

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195 since deposited on 07 Nov 2013
59 in the past twelve months

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ID Code: 64112
Item Type: QUT Thesis (Masters by Research)
Supervisor: Schuetz, Michael & Steck, Roland
Keywords: animal model, fracture, musculoskeletal infection, prosthetic, orthopaedics, osteomyelitis, rabbit
Divisions: Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > Institutes > Institute of Health and Biomedical Innovation
Current > QUT Faculties and Divisions > Science & Engineering Faculty
Institution: Queensland University of Technology
Deposited On: 07 Nov 2013 23:19
Last Modified: 07 Sep 2015 22:37

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