Improving in vivo models of fracture fixation associated osteomyelitis
Calabro, Lorenzo (2013) Improving in vivo models of fracture fixation associated osteomyelitis. Masters by Research thesis, Queensland University of Technology.
This project’s aim was to create new experimental models in small animals for the investigation of infections related to bone fracture fixation implants. Animal models are essential in orthopaedic trauma research and this study evaluated new implants and surgical techniques designed to improve standardisation in these experiments, and ultimately to minimise the number of animals needed in future work. This study developed and assessed procedures using plates and inter-locked nails to stabilise fractures in rabbit thigh bones. Fracture healing was examined with mechanical testing and histology. The results of this work contribute to improvements in future small animal infection experiments.
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|Item Type:||QUT Thesis (Masters by Research)|
|Supervisor:||Schuetz, Michael & Steck, Roland|
|Keywords:||animal model, fracture, musculoskeletal infection, prosthetic, orthopaedics, osteomyelitis, rabbit|
|Divisions:||Current > Schools > School of Chemistry, Physics & Mechanical Engineering
Current > Institutes > Institute of Health and Biomedical Innovation
Current > QUT Faculties and Divisions > Science & Engineering Faculty
|Institution:||Queensland University of Technology|
|Deposited On:||07 Nov 2013 23:19|
|Last Modified:||07 Sep 2015 22:37|
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