Epidemiological trend of hepatitis B, liver cirrhosis and liver cancer during 1990 - 2007 in Shandong province, China [山东省乙型肝炎、肝硬化及肝癌流行趋势分析]

Qi, Wenting, Sun, Jiandong, Xu, Aiqiang, Zhang, Li, Ma, Jixiang, Guo, XiaoLei, Yan, Bingyu, Fan, Qingying, & Yang, He (2009) Epidemiological trend of hepatitis B, liver cirrhosis and liver cancer during 1990 - 2007 in Shandong province, China [山东省乙型肝炎、肝硬化及肝癌流行趋势分析]. Chinese Journal of Public Health [中国公共卫生], 25(4), pp. 389-391.

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To analyze the epidemiological trend of hepatitis B, liver cirrhosis and liver cancer during 1990 to 2007 in Shandong province, and to evaluate the effectiveness of hepatitis B prevention and control measures, so as to provide evidence for policy-making.


Based on the routine incidence data of hepatitis B, mortality data of hepatitis B, liver cirrhosis, liver cancer and demographic data, the incidence rate, mortality rate and age-specific mortality rate were calculated and analyzed with simple linear regression model.


A total of 437094 cases of hepatitis B were reported during 1990 - 2007 with an average yearly morbidity of 27.32 per 100 000 persons and a decreased trend for the 0-9 years old children. At the same time, the adjusted mortality rate for hepatitis B and liver cirrhosis showed a decreased trend and the combined mortality rate decreased from 17.55 /100 000 in 1990 to 4.01 /100 000 in 2007. The mortality of liver cancer was stable during this time (P = 0. 9998).


Immunization of hepatitis B vaccine may have lowered the incidence of hepatitis B in the target population and the overall mortality rates of liver cirrhosis and liver cancer.

Abstract in Chinese






1990~2007年山东省共报告乙肝病例437 094例,年均总发病率为27.32/10万,并呈上升趋势,而0~9岁年龄组的发病率呈显著下降趋势.乙肝和肝硬化调整死亡率下降趋势明显,两者合并死亡率由1990年的17.55/10万下降到2007年的4.01/10万.肝癌调整死亡率基本稳定(P=0.999 8).



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ID Code: 64672
Item Type: Journal Article
Refereed: Yes
Additional Information: Authors: 亓文婷; 孙建东; 徐爱强; 张丽; 马吉祥; 郭晓雷; 颜丙玉; 樊庆莹; 杨赫;
Keywords: hepatitis B, liver cirrhosis, liver cancer, epidemiological trend, 乙肝, 肝硬化, 肝癌, 流行趋势
ISSN: 1001-0580
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Current > Schools > School of Public Health & Social Work
Deposited On: 27 Nov 2013 23:04
Last Modified: 08 Oct 2014 01:07

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