Investigation of genetic diversity and development of vaccine for Chlamydia pecorum infections in koala (Phascolarctos cinereus)
Kollipara, Avinash (2013) Investigation of genetic diversity and development of vaccine for Chlamydia pecorum infections in koala (Phascolarctos cinereus). PhD by Publication, Queensland University of Technology.
Many wild koala populations in Australia continue to experience serious declines due to factors such as disease caused by Chlamydia. This thesis is the first of its kind to investigate diversity of the chlamydial infections in wild koala populations across Australia and has made significant progress towards the development of a vaccine for koalas. The findings in this study have demonstrated that it is feasible to develop a safe and effective recombinant vaccine against Chlamydia in both disease free as well as severely diseased koalas. Most importantly, this study is also first of its kind to evaluate a multi-component vaccine that should be effective against the range of Chlamydia pecorum strains circulating in both captive as well as wild koala populations.
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|Item Type:||QUT Thesis (PhD by Publication)|
|Supervisor:||Timms, Peter, Beagley, Kenneth, & Polkinghorne, Adam|
|Keywords:||chlamydia , pecorum, Koala, vaccine, genetic diversity|
|Divisions:||Current > Schools > School of Biomedical Sciences
Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
|Institution:||Queensland University of Technology|
|Deposited On:||08 Jan 2014 02:04|
|Last Modified:||07 Sep 2015 01:06|
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