Gene silencing as an adaptive defence against viruses
Waterhouse, P. M., Wang, M. B., & Lough, T. (2001) Gene silencing as an adaptive defence against viruses. Nature, 411(6839), pp. 834-842.
Gene silencing was perceived initially as an unpredictable and inconvenient side effect of introducing transgenes into plants. It now seems that it is the consequence of accidentally triggering the plant's adaptive defence mechanism against viruses and transposable elements. This recently discovered mechanism, although mechanistically different, has a number of parallels with the immune system of mammals.
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|Item Type:||Journal Article|
|Keywords:||adaptation, gene silencing, immune system, infection resistance, nonhuman, plant, priority journal, review, RNA degradation, transgene, transposon, virus infection, Animals, DNA Transposable Elements, Gene Expression Regulation, Plant, Methylation, Plant Diseases, Plant Viruses, Plants, Ribonucleases, RNA, Antisense, RNA, Small Interfering, RNA, Viral, Mammalia|
|Divisions:||Current > Schools > School of Earth, Environmental & Biological Sciences
Current > QUT Faculties and Divisions > Science & Engineering Faculty
|Copyright Owner:||Nature Publishing Group|
|Deposited On:||08 Jan 2014 04:34|
|Last Modified:||08 Jan 2014 04:34|
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